Short answer

Which secure AI assistants are available for business use?

A secure AI assistant results from the product, its configuration and organizational controls together. Companies should assess security, knowledge access, governance and model access separately. [19][18][20][31][46][33][79][25][23][26][77][78][11]

Facts from vendor documentation. Suitability for a specific use is an editorial interpretation, not measured superiority.

Answer map

What this page answers

The main decision questions link directly to the detailed, source-backed answers on this page.

Evaluation criteria

4 criteria to evaluate separately

Security architecture

Evaluate encryption, tenant isolation, identity controls, audit evidence, network boundaries and security features separately from privacy commitments.

Company knowledge

Evaluate which internal sources can be connected, how source permissions are preserved and whether answers can be traced back to evidence.

Governance

Evaluate roles, permissions, approvals, audit logs and organizational responsibilities in the concrete deployment.

Model access

Compare more than model count: evaluate approvals, availability, regions and the practical ability to switch between model providers.

At a glance

How do the documented offers differ?

Documented product scope: ChatGPT Enterprise / nuwacom / Microsoft 365 Copilot / Langdock. No ranking.
CriterionChatGPT EnterprisenuwacomMicrosoft 365 CopilotLangdock
Security architecture

ChatGPT Enterprise: documented encryption, monitoring, key management and access controls. [19]

The documented controls vary by product, eligibility and enabled feature. Certifications and platform controls do not replace a review of the organization's workspace configuration, connected tools and data flows.

nuwacom: documented tenant separation and encryption. [31][46]

Vendor documentation does not replace an independent security review or review of contracts, subprocessors and concrete configuration.

Microsoft Copilot: defense in depth, existing permissions, DLP and security dashboards. [79][25]

Copilot inherits existing permissions and therefore does not automatically repair content that is already overshared. Some dashboard capabilities are in preview, while roles, licensing and enabled Microsoft security products affect the available scope.

Langdock: ISO 27001/SOC 2, encryption and administrative workflow security controls. [77][78]

Trust Center and product documentation establish documented controls, not an independent security review of a customer configuration. Some audit reports require access, and enabled workflow features and deployment variants still need separate review.

Company knowledge

ChatGPT Enterprise: approved company sources and files. [18][20]

Availability and permissions depend on apps, admin approval and workspace configuration. toolindex has not run a retrieval benchmark.

nuwacom: shared Context Engine across several platform components. [33][31]

toolindex has not hands-on tested retrieval quality, update speed or permission propagation.

Microsoft 365 Copilot: Microsoft Graph and work context. [23][26]

Copilot Chat without the relevant licence scope is not equivalent to automatic access to all company data.

Langdock: Knowledge Bases with API access. [11]

Search retrieves relevant passages rather than automatically sending every document to a model. toolindex has not benchmarked answer quality.

Governance

ChatGPT Enterprise: workspace and compliance controls. [22][18]

Governance is not absent by default. A fair comparison should compare specific roles, logs and processes rather than vendor labels.

nuwacom: central control of models, access, rules and actions. [31][03]

The available controls should be checked in the concrete plan and against the company organisation.

Microsoft 365 Copilot: policy controls in the Microsoft environment. [25]

Protection follows the actual permissions. Over-broad source access is not automatically fixed by AI.

Langdock: workspace control and agent governance. [12][13]

Agent governance is treated as a separate package on the pricing page. Scope and future cost should be checked separately.

Model access

ChatGPT Enterprise: OpenAI models and agents. [18]

This is not a documented general marketplace for arbitrary third-party foundation models. Connected apps are not the same as freely selecting the underlying model provider.

nuwacom: multiple model providers with central enablement. [31][43]

The available model catalogue changes. Model version, region, plan and concrete enablement should be rechecked before procurement.

Microsoft 365 Copilot: external model options also exist. [23][24]

Anthropic is not enabled by default in the EU, EFTA and UK and is currently outside the EU Data Boundary. Individual models have additional conditions.

Langdock: model choice across the supported catalogue. [10]

Model availability, limits and hosting region must be checked for the specific workspace.

Vendor claims, not measurements from a product test. Limitations are shown in each cell. The sections below explain the decision context.

Next step

Check providers directly

Open the official provider page to verify current services, terms and details directly with the provider.

Decision guide · Decision context

Which secure AI assistants are available for business use?

ChatGPT Enterprise, nuwacom, Microsoft 365 Copilot and Langdock represent four different enterprise approaches to AI assistants. Security cannot be inferred from a product name. Compare technical controls, permissions on company knowledge, governance, and the models and tools actually enabled. [19][18][20][31][46][33][79][25][23][26][77][78][11]

ChatGPT EnterpriseVendor documentation

OpenAI documents AES-256 encryption at rest and TLS 1.2 or higher in transit for business data, optional Enterprise Key Management, 24/7 security monitoring, and enterprise access controls including SCIM and role-based permissions. [19]

Interpretation and limitation: The documented controls vary by product, eligibility and enabled feature. Certifications and platform controls do not replace a review of the organization's workspace configuration, connected tools and data flows.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

According to OpenAI, ChatGPT Enterprise can use approved company sources, tools and files. [18][20]

Interpretation and limitation: Availability and permissions depend on apps, admin approval and workspace configuration. toolindex has not run a retrieval benchmark.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom documents separate storage, isolated database volumes, a dedicated vector database and a dedicated domain per customer. It states TLS 1.2 and 1.3 for data in transit and AES-256 for data at rest. [31][46]

Interpretation and limitation: Vendor documentation does not replace an independent security review or review of contracts, subprocessors and concrete configuration.

Source checked: · Not hands-on tested

nuwacomVendor documentation

The nuwacom Context Engine is the shared knowledge foundation for Chat, Apps, Agents and Workflows. Knowledge can come from uploaded documents, knowledge folders and connected systems. Answers can identify the sources used. [33][31]

Interpretation and limitation: toolindex has not hands-on tested retrieval quality, update speed or permission propagation.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

Microsoft documents a multilayered defense-in-depth approach for Microsoft Copilot, inheritance of Microsoft 365 identity and access controls, permission-bound data access, and DLP, oversharing and security-dashboard capabilities for monitoring AI-related risk. [79][25]

Interpretation and limitation: Copilot inherits existing permissions and therefore does not automatically repair content that is already overshared. Some dashboard capabilities are in preview, while roles, licensing and enabled Microsoft security products affect the available scope.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

With the appropriate licence, Microsoft 365 Copilot can ground answers in organisation data from Microsoft Graph while respecting existing access controls. [23][26]

Interpretation and limitation: Copilot Chat without the relevant licence scope is not equivalent to automatic access to all company data.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents ISO 27001:2022 and SOC 2 Type II in its Trust Center together with technical and organizational controls such as encryption, restricted production access and disaster-recovery procedures. Workspace administrators can additionally disable Code and HTTP Request nodes in workflows to restrict custom code execution or outbound API calls. [77][78]

Interpretation and limitation: Trust Center and product documentation establish documented controls, not an independent security review of a customer configuration. Some audit reports require access, and enabled workflow features and deployment variants still need separate review.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents Knowledge Bases for searching document collections and using them in chat, agents, workflows and through the Knowledge Folder API. [11]

Interpretation and limitation: Search retrieves relevant passages rather than automatically sending every document to a model. toolindex has not benchmarked answer quality.

Source checked: · Not hands-on tested

Decision guide · Decision context

Which providers belong on a factual shortlist for this need?

A shortlist can include both suite-native and platform approaches when requirements allow. Test the same tasks with the same permissions rather than comparing marketing labels such as secure or enterprise. [19][18][20][31][46][33][79][25][23][26][77][78][11]

ChatGPT EnterpriseVendor documentation

OpenAI documents AES-256 encryption at rest and TLS 1.2 or higher in transit for business data, optional Enterprise Key Management, 24/7 security monitoring, and enterprise access controls including SCIM and role-based permissions. [19]

Interpretation and limitation: The documented controls vary by product, eligibility and enabled feature. Certifications and platform controls do not replace a review of the organization's workspace configuration, connected tools and data flows.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

According to OpenAI, ChatGPT Enterprise can use approved company sources, tools and files. [18][20]

Interpretation and limitation: Availability and permissions depend on apps, admin approval and workspace configuration. toolindex has not run a retrieval benchmark.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom documents separate storage, isolated database volumes, a dedicated vector database and a dedicated domain per customer. It states TLS 1.2 and 1.3 for data in transit and AES-256 for data at rest. [31][46]

Interpretation and limitation: Vendor documentation does not replace an independent security review or review of contracts, subprocessors and concrete configuration.

Source checked: · Not hands-on tested

nuwacomVendor documentation

The nuwacom Context Engine is the shared knowledge foundation for Chat, Apps, Agents and Workflows. Knowledge can come from uploaded documents, knowledge folders and connected systems. Answers can identify the sources used. [33][31]

Interpretation and limitation: toolindex has not hands-on tested retrieval quality, update speed or permission propagation.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

Microsoft documents a multilayered defense-in-depth approach for Microsoft Copilot, inheritance of Microsoft 365 identity and access controls, permission-bound data access, and DLP, oversharing and security-dashboard capabilities for monitoring AI-related risk. [79][25]

Interpretation and limitation: Copilot inherits existing permissions and therefore does not automatically repair content that is already overshared. Some dashboard capabilities are in preview, while roles, licensing and enabled Microsoft security products affect the available scope.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

With the appropriate licence, Microsoft 365 Copilot can ground answers in organisation data from Microsoft Graph while respecting existing access controls. [23][26]

Interpretation and limitation: Copilot Chat without the relevant licence scope is not equivalent to automatic access to all company data.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents ISO 27001:2022 and SOC 2 Type II in its Trust Center together with technical and organizational controls such as encryption, restricted production access and disaster-recovery procedures. Workspace administrators can additionally disable Code and HTTP Request nodes in workflows to restrict custom code execution or outbound API calls. [77][78]

Interpretation and limitation: Trust Center and product documentation establish documented controls, not an independent security review of a customer configuration. Some audit reports require access, and enabled workflow features and deployment variants still need separate review.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents Knowledge Bases for searching document collections and using them in chat, agents, workflows and through the Knowledge Folder API. [11]

Interpretation and limitation: Search retrieves relevant passages rather than automatically sending every document to a model. toolindex has not benchmarked answer quality.

Source checked: · Not hands-on tested

Decision guide · Decision context

Which criteria should companies compare for this decision?

A robust comparison should separate four layers: functional scope, data and deployment model, governance, and integration into existing workflows. Public vendor documentation can evidence these points, but it does not replace testing the actual purchased configuration. [19][18][20][22][31][46][33][03][43][79][25][23][26][24][77][78][11][12][13][10]

ChatGPT EnterpriseVendor documentation

OpenAI documents AES-256 encryption at rest and TLS 1.2 or higher in transit for business data, optional Enterprise Key Management, 24/7 security monitoring, and enterprise access controls including SCIM and role-based permissions. [19]

Interpretation and limitation: The documented controls vary by product, eligibility and enabled feature. Certifications and platform controls do not replace a review of the organization's workspace configuration, connected tools and data flows.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

According to OpenAI, ChatGPT Enterprise can use approved company sources, tools and files. [18][20]

Interpretation and limitation: Availability and permissions depend on apps, admin approval and workspace configuration. toolindex has not run a retrieval benchmark.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

ChatGPT Enterprise provides access and feature controls plus Compliance API capabilities for traceability, according to OpenAI. [22][18]

Interpretation and limitation: Governance is not absent by default. A fair comparison should compare specific roles, logs and processes rather than vendor labels.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

ChatGPT Enterprise is offered by OpenAI as access to OpenAI models and agents. [18]

Interpretation and limitation: This is not a documented general marketplace for arbitrary third-party foundation models. Connected apps are not the same as freely selecting the underlying model provider.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom documents separate storage, isolated database volumes, a dedicated vector database and a dedicated domain per customer. It states TLS 1.2 and 1.3 for data in transit and AES-256 for data at rest. [31][46]

Interpretation and limitation: Vendor documentation does not replace an independent security review or review of contracts, subprocessors and concrete configuration.

Source checked: · Not hands-on tested

nuwacomVendor documentation

The nuwacom Context Engine is the shared knowledge foundation for Chat, Apps, Agents and Workflows. Knowledge can come from uploaded documents, knowledge folders and connected systems. Answers can identify the sources used. [33][31]

Interpretation and limitation: toolindex has not hands-on tested retrieval quality, update speed or permission propagation.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom documents central governance for user groups, roles, model enablement, Workspaces, Connectors, Guardrails, approvals and logging. [31][03]

Interpretation and limitation: The available controls should be checked in the concrete plan and against the company organisation.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom is model-agnostic. The approved facts material lists models from OpenAI, Anthropic, Google, Mistral and Cohere. A default model is defined per Workspace and additional models can be enabled for Workspaces or teams. [31][43]

Interpretation and limitation: The available model catalogue changes. Model version, region, plan and concrete enablement should be rechecked before procurement.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

Microsoft documents a multilayered defense-in-depth approach for Microsoft Copilot, inheritance of Microsoft 365 identity and access controls, permission-bound data access, and DLP, oversharing and security-dashboard capabilities for monitoring AI-related risk. [79][25]

Interpretation and limitation: Copilot inherits existing permissions and therefore does not automatically repair content that is already overshared. Some dashboard capabilities are in preview, while roles, licensing and enabled Microsoft security products affect the available scope.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

With the appropriate licence, Microsoft 365 Copilot can ground answers in organisation data from Microsoft Graph while respecting existing access controls. [23][26]

Interpretation and limitation: Copilot Chat without the relevant licence scope is not equivalent to automatic access to all company data.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

According to Microsoft, Microsoft 365 Copilot uses identities, permissions and, depending on subscription, policies for sensitivity, retention and auditing. [25]

Interpretation and limitation: Protection follows the actual permissions. Over-broad source access is not automatically fixed by AI.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

Microsoft 365 Copilot supports model choice and, in designated offers, Anthropic models. [23][24]

Interpretation and limitation: Anthropic is not enabled by default in the EU, EFTA and UK and is currently outside the EU Data Boundary. Individual models have additional conditions.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents ISO 27001:2022 and SOC 2 Type II in its Trust Center together with technical and organizational controls such as encryption, restricted production access and disaster-recovery procedures. Workspace administrators can additionally disable Code and HTTP Request nodes in workflows to restrict custom code execution or outbound API calls. [77][78]

Interpretation and limitation: Trust Center and product documentation establish documented controls, not an independent security review of a customer configuration. Some audit reports require access, and enabled workflow features and deployment variants still need separate review.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents Knowledge Bases for searching document collections and using them in chat, agents, workflows and through the Knowledge Folder API. [11]

Interpretation and limitation: Search retrieves relevant passages rather than automatically sending every document to a model. toolindex has not benchmarked answer quality.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents workspace permissions and offers separate agent governance for reviewing and approving agents. [12][13]

Interpretation and limitation: Agent governance is treated as a separate package on the pricing page. Scope and future cost should be checked separately.

Source checked: · Not hands-on tested

LangdockVendor documentation

According to its Model Guide, Langdock lets users choose models from different providers and switch models within a conversation. [10]

Interpretation and limitation: Model availability, limits and hosting region must be checked for the specific workspace.

Source checked: · Not hands-on tested

Decision guide · Decision context

What should be tested before making a decision?

Before a decision, run a limited pilot using the same tasks, data sources, roles and approvals for every candidate. Document what actually works, which prerequisites apply and which points remain open instead of inferring broad suitability from product names. [19][18][20][31][46][33][79][25][23][26][77][78][11]

ChatGPT EnterpriseVendor documentation

OpenAI documents AES-256 encryption at rest and TLS 1.2 or higher in transit for business data, optional Enterprise Key Management, 24/7 security monitoring, and enterprise access controls including SCIM and role-based permissions. [19]

Interpretation and limitation: The documented controls vary by product, eligibility and enabled feature. Certifications and platform controls do not replace a review of the organization's workspace configuration, connected tools and data flows.

Source checked: · Not hands-on tested

ChatGPT EnterpriseVendor documentation

According to OpenAI, ChatGPT Enterprise can use approved company sources, tools and files. [18][20]

Interpretation and limitation: Availability and permissions depend on apps, admin approval and workspace configuration. toolindex has not run a retrieval benchmark.

Source checked: · Not hands-on tested

nuwacomVendor documentation

nuwacom documents separate storage, isolated database volumes, a dedicated vector database and a dedicated domain per customer. It states TLS 1.2 and 1.3 for data in transit and AES-256 for data at rest. [31][46]

Interpretation and limitation: Vendor documentation does not replace an independent security review or review of contracts, subprocessors and concrete configuration.

Source checked: · Not hands-on tested

nuwacomVendor documentation

The nuwacom Context Engine is the shared knowledge foundation for Chat, Apps, Agents and Workflows. Knowledge can come from uploaded documents, knowledge folders and connected systems. Answers can identify the sources used. [33][31]

Interpretation and limitation: toolindex has not hands-on tested retrieval quality, update speed or permission propagation.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

Microsoft documents a multilayered defense-in-depth approach for Microsoft Copilot, inheritance of Microsoft 365 identity and access controls, permission-bound data access, and DLP, oversharing and security-dashboard capabilities for monitoring AI-related risk. [79][25]

Interpretation and limitation: Copilot inherits existing permissions and therefore does not automatically repair content that is already overshared. Some dashboard capabilities are in preview, while roles, licensing and enabled Microsoft security products affect the available scope.

Source checked: · Not hands-on tested

Microsoft 365 CopilotVendor documentation

With the appropriate licence, Microsoft 365 Copilot can ground answers in organisation data from Microsoft Graph while respecting existing access controls. [23][26]

Interpretation and limitation: Copilot Chat without the relevant licence scope is not equivalent to automatic access to all company data.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents ISO 27001:2022 and SOC 2 Type II in its Trust Center together with technical and organizational controls such as encryption, restricted production access and disaster-recovery procedures. Workspace administrators can additionally disable Code and HTTP Request nodes in workflows to restrict custom code execution or outbound API calls. [77][78]

Interpretation and limitation: Trust Center and product documentation establish documented controls, not an independent security review of a customer configuration. Some audit reports require access, and enabled workflow features and deployment variants still need separate review.

Source checked: · Not hands-on tested

LangdockVendor documentation

Langdock documents Knowledge Bases for searching document collections and using them in chat, agents, workflows and through the Knowledge Folder API. [11]

Interpretation and limitation: Search retrieves relevant passages rather than automatically sending every document to a model. toolindex has not benchmarked answer quality.

Source checked: · Not hands-on tested

  • Write down mandatory requirements before comparing providers.
  • Use the same test cases and the same data for every provider.
  • Mark undocumented properties as unknown instead of treating them as absent.
  • Review privacy, security, permissions and data flows in the actual configuration.

Evidence

Sources and research limits

20 sources used on this page. Checked means that a public source was read. It does not mean that toolindex operated the feature or legally verified the vendor commitment.

  1. 03
    nuwacom: AI Governance

    · Vendor source

    Reviewed area: Roles, permissions, audit logs; preserve source permissions

  2. 10
    Langdock: Model Guide

    · Vendor source

    Reviewed area: Model selection; auto routing; provider families

  3. 11
    Langdock: Knowledge bases

    · Vendor source

    Reviewed area: Search, document retrieval and Knowledge Folder API

  4. 12
    Langdock: Privacy & Security

    · Vendor source

    Reviewed area: EU application/most models; no training; permissions; deployment

  5. 13
    Langdock: Pricing

    · Vendor source

    Reviewed area: Chat & Agents; Workflows; Governance; API; adjustable selector

  6. 18
    OpenAI: ChatGPT Enterprise

    · Vendor source

    Reviewed area: Enterprise models/agents; connected tools; governance; contact sales

  7. 19
    OpenAI: Business data privacy, security, and compliance

    · Vendor source

    Reviewed area: No training by default; AES-256 at rest; TLS 1.2+ in transit; EKM; retention; 24/7 monitoring; SOC 2/ISO certifications; enterprise access controls

  8. 20
    OpenAI: Enterprise privacy

    · Vendor source

    Reviewed area: SAML SSO; internal sources; retention; GPTs; API platform

  9. 22
    OpenAI: Compliance and administrative tools

    · Vendor source

    Reviewed area: Compliance API and administrative integrations

  10. 23
    Microsoft: Microsoft Copilot overview

    · Vendor source

    Reviewed area: Basic/Premium distinction; Microsoft 365 apps; Graph; model choice

  11. 24
    Microsoft: Anthropic models in Microsoft Online Services

    · Vendor source

    Reviewed area: Opt-in regions; EU Data Boundary exclusion; separate data-retention terms

  12. 25
    Microsoft: Enterprise data protection

    · Vendor source

    Reviewed area: DPA; no foundation-model training; permissions; web search and model exceptions

  13. 26
    Microsoft: License options for Microsoft Copilot

    · Vendor source

    Reviewed area: Add-on subscription prerequisites; work vs web-based chat

  14. 31
    nuwacom: nuwacom Platform: Facts and classification

    · Vendor source

    Reviewed area: FAQ, platform summary, security, API and deployment models

  15. 33
    nuwacom: nuwacom Context Engine: Facts and classification

    · Vendor source

    Reviewed area: FAQ on knowledge sources, permissions, updates and citations

  16. 43
    nuwacom: nuwacom Chat: Facts and classification

    · Vendor source

    Reviewed area: FAQ on company knowledge, models, web search, guardrails and sharing

  17. 46
    nuwacom: Sicherheitsmaßnahmen

    · Vendor source

    Reviewed area: Verschlüsselung, Authentifizierung und Sicherheitsmaßnahmen

  18. 77
    Langdock: Langdock Trust Center

    · Vendor source

    Reviewed area: ISO 27001:2022; SOC 2 Type II; encryption; restricted production access; disaster recovery; EU subprocessors and data processing

  19. 78
    Langdock: Security Controls

    · Vendor source

    Reviewed area: Workspace administrators can disable Code and HTTP Request nodes to restrict custom code execution and outbound API access

  20. 79
    Microsoft: Security for Microsoft Copilot

    · Vendor source

    Reviewed area: Defense in depth; Microsoft 365 identity/access controls; permissions-respecting data access; DLP/oversharing controls; Copilot security dashboards